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CAS NO.1113-41-3
●Reference price:USD12000 for 1kg FOB Shanghai(update date:2021.01.31)
Product name:L-Penicillamine
Synonym:penicillamine impurity 4(l-penicillamine);(2r)-2-amino-3-methyl-3-sulfanylbutanoic acid; 3-mercapto-l-valine;3-thiol-valine;3,3-dimethyl-l-cysteine;l-beta,beta-dimethylcysteine;l-beta-mercaptovaline;l-(+)-penicillamine
Cas No: 1113-41-3
Molecular Formula:C5H11NO2S
Molecular Weight:149.21
Appearance:Off white to white powder
Purity:99% min
Optical purity (Derivatization HPLC method):99.5% min
Loss on drying:1.0%max
Specific rotation(c=1,1M NaOH)[20/D]:+63°±2.0°
Boiling point: 251.8±35.0 °C
Density:1.113
Refractive index:63 ° (C=1, 1mol/L NaOH)
HS Code:2930909099
About the introduction of L-Penicillamine:
●Description:With the rapid development of science and technology, people's demand for drugs is becoming more and more urgent. In recent decades, the variety of diseases has been increasing, and the emergence of L-penicillamine has brought new eyebrows to the research and development of medical science and technology.
L-penicillamine (C5H11NO2S, L-(+) -penicillamine) is prepared by acylation, resolution and hydrolysis of D-penicillamine. It is a white solid with a melting point of 206 degrees Celsius and is soluble. It is stable at room temperature and pressure and avoids contact with reinforcements. L-penicillamine is toxic and slightly harmful to water. Do not expose undiluted or large quantities of products to groundwater, waterways or sewage systems. Do not discharge materials into the surrounding environment without government permission.
L-penicillamine (cas: 1113-41-3) is a key intermediate of many drugs. It has broad market prospects, such as the synthesis of protease inhibitors against AIDS (je-1520, je-2147). At present, both drugs are in the stage of clinical trials and have good antiviral efficacy. At the same time, they are also the cardiovascular drug sd3321 and the anticancer drug ag3. 340 is an important intermediate.
●Uses:L-Penicillamine is a metabolite of penicillin. L-Penicillamine is used in the treatment of Wilson Holmium Disease, Cystinuria, Scleroderma and arsenic poisoning.
●Storage:keep sealed and keep from direct light
Hangzhou ZeErRui Chemical Co., Ltd. is focused on customization, research and development and production of APIs and advanced intermediates, which can effectively compensate for the deficiencies of traditional CRO and CMO. Priority of high-tech barriers, high value-added, low pollution characteristics of the project, landing the project of innovative non patented route design, difficult process development and rapid industrialization. Starting from the advantages of combining technology research and stable production, Lead Biotech cooperated with domestic and foreign large pharmaceutical companies in the development of generic drugs and innovative drugs.
It also has hardware facilities and support teams that match the strength of R & D and production: With LCMS, HPLC and other perfect detection means, professional testing team and perfect quality control system; With a pilot base, a stable GMP standard production capacity, and a new GMP workshop is building; With regular financial, legal ERP system and professional sales and logistics team.