Dofetilide manufature CAS NO.115256-11-6

ProductName:dofetilide

Synonyms:Dofetilidum;Xelide;N-[4-[2-[2-[4-(methanesulfonamido)phenoxy]ethyl-methylamino]ethyl]phenyl]methanesulfonamide;Dofetilide;1-MSPMPE;Dofetilida;

Tikosyn;

CAS:115256-11-6

Molecular Formula: C19H27N3O5S2

Molecular Weight:441.56500

Purity:≥99%

Appearance and properties: gray white or light yellow crystalline powder            Density: 1.344 g / cm1.344 g / cm3            

Boiling point: 614.1 ° C at 760 mmHg            

Melting point: 147-1490c            

Flash point: 325.2 ° C

Introduction:Dofetilide is a class III antiarrhythmic agent. It is marketed under the trade name Tikosyn by Pfizer, and is available in the United States in capsules containing 125, 250, and 500 µg of dofetilide. It is not available in Europe or Australia.
Due to the pro-arrhythmic potential of dofetilide, it is only available by prescription from physicians who have undergone specific training in the risks of treatment with dofetilide. In addition, it is only available by mail order or through specially trained local pharmacies.

Hangzhou ZeErRui Chemical Co., Ltd. is focused on customization, research and development and production of APIs and advanced intermediates, which can effectively compensate for the deficiencies of traditional CRO and CMO. Priority of high-tech barriers, high value-added, low pollution characteristics of the project, landing the project of innovative non patented route design, difficult process development and rapid industrialization.  Starting from the advantages of combining technology research and stable production, we cooperated with domestic and foreign large pharmaceutical companies in the development of generic drugs and innovative drugs.

It also has hardware facilities and support teams that match the strength of R & D and production: With LCMS, HPLC and other perfect detection means, professional testing team and perfect quality control system; With a pilot base, a stable GMP standard production capacity, and a new GMP workshop is building; With regular financial, legal ERP system and professional sales and logistics team.