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CAS NO.143527-70-2
Hangzhou ZeErRui Chemical Co., Ltd. is a leading company that is focused on developing and producing high-quality flavor ingredients used for foods, pharmaceutic, cosmetics, and daily-use goods. Our goal is to produce flavor ingredients through sciences and further to provide our flavor ingredients to products that can delight human life quality.
ZER Chem has capacity to supply more than 200 high-quality flavor ingredients to our customers. Our R&D team works tirelessly and innovatively to develop and customize flavor ingredients to satisfy the needs of our customers. We look forward to collaborating with our customers to bring the best flavor ingredients to the world.
Product name:(4S,5R)-3-(tert-Butoxycarbonyl)-2,2-dimethyl-4-phenyloxazolidine-5-carboxylic acid
Synonyms:(4s-trans)-2,2-dimethyl-4-phenyl-3,5-oxazolidinedicarboxylicacid3-(1,1-dimethylethyl)ester;(4S,5R)-3,5-OXAZOLIDINEDICARBOXYLICACID-2,2-DIMETHYL-4-PHENYL-3-(1,1-DIMETHYLETHYL)ESTER;(4S,5R)-3,5-Oxazolidinedicarbo;(4S,5R)-3-(tert-butoxycarbonyl)-2,2-dimethyl-4-phenyloxazolidine-5-carboxylic;(4S,5R)-3-(N-tert-butoxycarbonyl)-2,2-dimethyl-4-phenyloxazolidine-5-carboxylicacid
CAS No:143527-70-2
Molecular formula:C17H23NO5
Molecular Weight:321.37
Appearance:white powders
Melting point 112.0 to 116.0 °C
Boiling point 459.0±45.0 °C(Predicted)
Density 1.177
Storage conditions Refrigerator
Paclitaxel and docetaxel are high-efficiency, low toxicity and broad-spectrum anticancer drugs, especially for gynecological tumors, so they are the fastest-growing chemotherapeutic drugs in clinical use. The C13 side chain of paclitaxel was slightly modified (that is, the benzoyl group of the side chain was changed to tert butoxycarbonyl) to obtain the side chain of docetaxel. Then the side chains of paclitaxel and docetaxel were coupled with baccatin III to obtain anticancer drugs paclitaxel and docetaxel, respectively.
The side chain of docetaxel can be used as an intermediate of organic synthesis and pharmaceutical intermediates. It is mainly used in laboratory research and development process and chemical pharmaceutical synthesis process. It can be used as an intermediate of docetaxel.