N-Carbethoxy-4-piperidone manufacture CAS NO.29976-53-2

ProductName:N-Carbethoxy-4-piperidone

Synonyms:ethyl 4-oxopiperidine-1-carboxylate;1-Piperidinecarboxylic acid, 4-oxo-, ethyl ester;1-Ethoxycarbonyl-4-piperidone;N-carboethoxy-4-piperidinone;

AURORA KA-3057;N-Carbethoxypiperidone;N-Carbethoxy-4-piperidon;

4-oxo-piperidine-1-carboxylic acid ethyl ester;1-Carbethoxy-4-piperidone;

Ethyl 4-Oxo-1-piperidinecarboxylate;4-Oxo-1-piperidinecarboxylic Acid Ethyl Ester;

LoratadineimpurityH;1-Carbethoxy-4-piperidone,1-Ethoxycarbonyl-4-piperidone,Ethyl 4-oxo-1-piperidinecarboxylate;1-ethoxycarbonyl-4-piperidinone;

1-carboethoxy-4-piperidone;carbethoxy-4-piperidone;N-ETHOXYCARBONYL-4-PIPERIDONE;N-Carbithoxy-4-Piperidone;N-CARBOETHOXY-4-PIPERIDONE;

CAS:29976-53-2

Molecular Formula: C8H13NO3

Molecular Weight:171.19400

Purity:≥98%

Appearance and character: colorless liquid            

Density: 1.135 g / ml at 25 ° C (lit.)            

Boiling point: 95-98 ° C (1 mmHg)            

Flash point: 190 ° f            

Refractive index: N20 / D 1.475 (lit.)            

Water solubility: slightly soluble            

Stability: stable under normal temperatures and pressures            

Keep away from sources of designation. Store in a tightly closed container. Store in a cool, dry, well vented area away from incompatible substances            

Vapor pressure: 0.00574mmhg at 25 ° C

Brief introduction：N-Carbethoxy-4-piperidone is used in the preparation of 3-hydrazinopyridazines as antihypertensive agents as well as γ-carboline derivatives as potential serotonergic agents. N-Carbethoxy-4-piperidone is also an impurity of Loratadine.

Hangzhou ZeErRui Chemical Co., Ltd. is focused on customization, research and development and production of APIs and advanced intermediates, which can effectively compensate for the deficiencies of traditional CRO and CMO. Priority of high-tech barriers, high value-added, low pollution characteristics of the project, landing the project of innovative non patented route design, difficult process development and rapid industrialization.  Starting from the advantages of combining technology research and stable production, we cooperated with domestic and foreign large pharmaceutical companies in the development of generic drugs and innovative drugs.

It also has hardware facilities and support teams that match the strength of R & D and production: With LCMS, HPLC and other perfect detection means, professional testing team and perfect quality control system; With a pilot base, a stable GMP standard production capacity, and a new GMP workshop is building; With regular financial, legal ERP system and professional sales and logistics team.