Praziquantel china manufacture CAS NO.55268-74-1

Hangzhou ZeErRui Chemical Co., Ltd. is a leading company that is focused on developing and producing high-quality flavor ingredients used for foods, pharmaceutic, cosmetics, and daily-use goods. Our goal is to produce flavor ingredients through sciences and further to provide our flavor ingredients to products that can delight human life quality.

ZER Chem has capacity to supply more than 200 high-quality flavor ingredients to our customers. Our R&D team works tirelessly and innovatively to develop and customize flavor ingredients to satisfy the needs of our customers. We look forward to collaborating with our customers to bring the best flavor ingredients to the world.

Product name:Praziquantel

Synonyms:4h-pyrazino(2,1-a)isoquinolin-4-one,2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexah;4H-pyrazino-[2,1-a]-isoquinolin-4-one,2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-;biltricide;droncit;Praziquantelforsystemsuitability;2-(Cyclohexanecarbonyl)-1，3，4，6，7，11b-hexahydro-4H-pyrazino[2，1-α]isoquinolin-4-one

CAS No:55268-74-1

Molecular formula:C19H24N2O2

Molecular Weight:312.41

Appearance:white powders

Melting point 136-138 ° C

Boiling point 1377℃

Density 1.1209 (rough estimate)

Storage conditions −20°C

Praziquantel, also known as cyclopyrisoquinolone, is a commonly used drug for the treatment of schistosomiasis. It has minimal toxicity to animals and is rapidly absorbed in the digestive tract after oral administration. The peak time of blood drug was 5 minutes in mice, 15-30 minutes in rats, 30-120 minutes in dogs and 2 hours in sheep. After absorption, the drug is widely distributed in all tissues and organs, even can pass through the blood-brain barrier of rats, and can enter the bile of dogs. It can promote the influx of Ca²⁺ outside the muscle cell membrane of Schistosoma japonicum, cause muscle contracture, and lose the ability to absorb parasitic parts. At the same time, it causes the disorder of glucose metabolism and energy metabolism, the state of "accompanying immunity" is destroyed, and then through the host immune system, the worm body is finally destroyed. The killing effect of Schistosoma, Taenia, Paragonimus, cysticercosis and immature worm body (cercariae and miracidia) is very good.

It is an effective anti worm drug against Schistosoma japonicum, Schistosoma mansoni, Schistosoma egyptosum, Clonorchis sinensis, Paragonimus, Fasciola, Taenia and cysticercosis. In particular, it has a strong killing effect on Taenia solium, and is one of the best schistosomiasis drugs.