EMpagliflozin manufacture CAS NO.864070-44-0

Product Name: empagliflozin            

Synonyms: x5927;    (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol; Empagliflozin;CS-0940;            

CAS No.: 864070-44-0           

Molecular formula: c23h27clo7            

Molecular weight: 450.90900

Brief introduction：Engglitazin is a new generation of SGLT2 inhibitor (type II sodium glucose transporter inhibitor). It was approved by the US Food and Drug Administration (FDA) in August 2014. It is used to treat adult type 2 diabetes with diet and exercise. "Engliptin" can reduce the kidney's ability to recover glucose back into the blood and excrete the sugar through the urine. It can significantly reduce the blood glucose level, kidney disease and cardiovascular disease risk, overweight and blood pressure. Different from other oral drugs currently used for the treatment of type 2 diabetes, "engglijing" is the first SGLT2 hypoglycemic drug to complete the cardiovascular prognosis study. It is also the only oral hypoglycemic drug, which has been proved to have the quadruple effects of glucose control, heart protection, kidney protection and weight loss.            "Empagliflozin" is a new generation of SGLT2 inhibitor complex developed by German pharmaceutical factory, with the trade name of "jardiance" and the Chinese trade name of "enpaitang" (Taiwan) or "Sitangda" (Hong Kong).

Hangzhou ZeErRui Chemical Co., Ltd. is focused on customization, research and development and production of APIs and advanced intermediates, which can effectively compensate for the deficiencies of traditional CRO and CMO. Priority of high-tech barriers, high value-added, low pollution characteristics of the project, landing the project of innovative non patented route design, difficult process development and rapid industrialization.  Starting from the advantages of combining technology research and stable production, we cooperated with domestic and foreign large pharmaceutical companies in the development of generic drugs and innovative drugs.

It also has hardware facilities and support teams that match the strength of R & D and production: With LCMS, HPLC and other perfect detection means, professional testing team and perfect quality control system; With a pilot base, a stable GMP standard production capacity, and a new GMP workshop is building; With regular financial, legal ERP system and professional sales and logistics team.