Business Type:Lab/Research institutions
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Country: China (Mainland)
Business Type:Lab/Research institutions
Tel: +86-571-82512721
Mobile: 8615067157489
Tel: +86-571-82512721
Fax: +86-571-57153510
URL: http://www.chinazerchem.com
Province/state: Zhejiang Province
City: Hangzhou City
Street: No 317,Jingling Road,Guali Town,Xiaoshan District
MaxCard:
ProductName:amlodipine
Synonyms:Norvasc;Lipinox;Amlodis;2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine;Amlodipino;
2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester;3-ethyl 5-methyl ()-2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridine dicarboxylate;Istin;(R,S)-2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine;Amlodipinum [Latin];
Amlodipinum;Amlocard;3-ethyl-5-methyl-(4RS)-2-[(2-aminoethoxy)-methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-carboxylate benzene sulphonate;
Coroval;
CAS:88150-42-9
Molecular Formula: C20H25ClN2O5
Molecular Weight:408.87600
Purity:≥99%
Appearance and character: yellow solid
Density: 1.227 g / cm3
Boiling point: 527.2 ° C at 760 mmHg
Melting point: 178-179 ° C
Storage conditions: - 20 ° C freezer
brief introduction:Amlodipine (amlodipine or amlodipine besylate, Norvasc, Pfizer trade name) and other scientific name drugs, can be prepared with benzene sulfonic acid (besylate), mesylate (mesylate) or maleic acid (maleic acid), etc. amlodipine (amlodipine or amlodipine besylate, trademark name of Norvasc, Pfizer company) and other scientific name drugs, is a kind of "long-term calcium channel blocker (CCB)" as an antihypertensive drug and dihydropyridine (DHP) class in the treatment of angina pectoris. Like other calcium channel blockers, amlodipine reduces the total peripheral resistance by relaxing the smooth muscle in the arterial wall In angina pectoris, amlodipine increases blood flow to the heart muscle (although "DHP calcium channel blockers" are more selective for arteries, such as "myocardial calcium channel blockers" do not have "dihydropyridine" type compared with cardiac muscle tissue).
Hangzhou ZeErRui Chemical Co., Ltd. is focused on customization, research and development and production of APIs and advanced intermediates, which can effectively compensate for the deficiencies of traditional CRO and CMO. Priority of high-tech barriers, high value-added, low pollution characteristics of the project, landing the project of innovative non patented route design, difficult process development and rapid industrialization. Starting from the advantages of combining technology research and stable production, we cooperated with domestic and foreign large pharmaceutical companies in the development of generic drugs and innovative drugs.
It also has hardware facilities and support teams that match the strength of R & D and production: With LCMS, HPLC and other perfect detection means, professional testing team and perfect quality control system; With a pilot base, a stable GMP standard production capacity, and a new GMP workshop is building; With regular financial, legal ERP system and professional sales and logistics team.